I'm the most comfortable in a car (that I'm driving), but it's about my least favorite way to get somewhere, because if you're going any distance, it takes too long to get there, and until I retire, we're always on a very limited vacation schedule (12 days maximum at one time).
Where I get stressed, really, is anything to do with a ticket or a reservation, like a plane or a train or a ship. I always imagine every little thing that can go wrong, and in my mind, that starts a chain of events that ultimately leads to me missing the plane/train/ship.
For example, my wife would be fine taking coach/economy, because for her, she's just going to sleep, and it's a means of getting there, nothing to be enjoyed on its own, so why bother with extra money to upgrade?
I insist on at least economy+ (called Comfort Class with our preferred airline), for the sole reason that it includes reserved overhead compartment space.
Why is that so important to me? Here's how my rat's nest brain works:
"Tasty, if you don't have dedicated overhead space, someone will have taken the space over your seat by the time you get on, and then the flight attendant will take your bag and find space far, far away in the back of the plane for your bag, which means you'll have to wait for everyone to exit before you can fight your way back there, and by the time you do that and get off the plane, you'll get to the car hire desk and find that, despite your reservation, they'll have no cars available (that's happened more than once to me), and then you'll have to find a train to get you somewhat close to your final destination, only all of the trains will be full, so you'll be stuck at the airport, and by the time you can finally find a car or a train leave the airport, you'll get to your hotel only to find they've given your room away because you were late and now it's 8PM and all the hotels are full and you haven't eaten since the morning because you've spent all your time trying to get transportation, and the restaurants have no space, especially for someone dragging luggage behind them, and now you're going to faint from hunger and once you wake up again, you'll find someone has stolen your luggage and all your money and the shoes you were wearing and now you look dirty and homeless and the police will arrest you and throw you into jail for loitering and you have no identification or passport, so now you're destined to die a nameless unknown derelict in some prison in whatever country you're in and no one will ever know what became of you. That's why you need dedicated overhead space."
. NYE 20/21
